The management of invasive candidiasis
- Invasive candidiasis is an additional and significant problem in ICU and haematology patients1-4
- Patients in the ICU have an increased risk of developing candidaemia compared with patients on medical or surgical wards4
- 40.2% of candidaemia occurs in the ICU5
- Delaying antifungal therapy can have fatal consequences4,6
- Comorbidities and the potential for multiple drug interactions from concomitant medications complicate treatment1,7,8
Mortality rate stratified by delay in initiation of antifungal therapy*6
ICU, intensive care unit
1. Najman A, et al. Bull Cancer 2009;96:563-570.
2. Murali S, Langston A. Transpl Infect Dis 2009;11:480-490.
3. Gamaletsou MN, et al. Clin Microbiol Infect 2014;20:050-057.
4. Delaloye J. Calandra T. Virulence 2014;5:154-162.
5. Tortorano AM, et al. ECMM Working Group on Candidaemia. Eur J Clin Microbiol Infect Dis
6. Morrell M, et al. Antimicrob Agents Chemother 2005; 49:3640-3645.
7. Papadopoulous J. Smithburger PL. Crit Care Med 2010; 38 Suppl 6: S126-135.
8. Perazella MA. Kidney Int 2012; 81:1172-1178.